Importance of pulmonary artery to ascending aorta ratio in chronic obstructive pulmonary disease
Copyright policy )Importance of pulmonary artery to ascending aorta ratio in chronic obstructive pulmonary disease
AbstractIntroductionRecent articles revealed that an increased main pulmonary artery to ascending aorta ratio (PA/A) in thorax computed tomography (CT) correlated with pulmonary hypertension, and might be linked to a high probability of chronic obstructive pulmonary disease (COPD) exacerbations.ObjectivesIn this study, our aim was to evaluate the clinical importance of PA/A in patients with exacerbations of COPD and investigate its relationship with the number of exacerbations in 1 year or short/long‐term mortality after hospital discharge.MethodsOne hundred fifty‐six patients hospitalized for COPD exacerbations who fulfilled our inclusion criteria were enrolled in the study. We recorded the number of exacerbations in 1 year from hospital records, checked mortality status, and calculated the PA/A ratio from thorax CT images.ResultsPA/A ratio positively correlated with the number of hospitalizations for COPD exacerbations and the total number of exacerbations (hospitalized or not) in 1 year, and baseline PaCO2 level during hospitalization (r = 0.376, P < 0.001, r = 0.230, P = 0.004, and r = 0.328, P < 0.001, respectively). There was no relationship between mortality and PA/A.ConclusionOur study showed that PA/A was related with the number of hospitalizations and the total number of exacerbations due to COPD in 1 year. However, there was no relationship between PA/A and mortality.
- Koç University Turkey
- Istanbul University Turkey
Aged, 80 and over, Male, Hypertension, Pulmonary, Middle Aged, Pulmonary Artery, Vascular Remodeling, Patient Discharge, Hospitalization, Pulmonary Disease, Chronic Obstructive, Echocardiography, Forced Expiratory Volume, Disease Progression, Humans, Female, Mortality, Tomography, X-Ray Computed, Aorta, Aged, Retrospective Studies
Aged, 80 and over, Male, Hypertension, Pulmonary, Middle Aged, Pulmonary Artery, Vascular Remodeling, Patient Discharge, Hospitalization, Pulmonary Disease, Chronic Obstructive, Echocardiography, Forced Expiratory Volume, Disease Progression, Humans, Female, Mortality, Tomography, X-Ray Computed, Aorta, Aged, Retrospective Studies
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