Isoforms of Protein Kinase C and Their Distribution in Human Adrenal Cortex and Tumors
Copyright policy )Isoforms of Protein Kinase C and Their Distribution in Human Adrenal Cortex and Tumors
The cytosol and microsomal fractions of human adrenal cortex contain 3 isoforms of protein kinase C: alpha, zeta, and epsilon. The latter fraction is present in trace amounts. No isoforms beta1, beta2, gamma and delta were found in these cell fractions. The distribution of alpha-isoform between the cytosol and microsomal fraction is determined by tissue origin: in normal tissue its content differs by no more than 10%, while in most tumors this isoform is translocated into the microsomal fraction. The distribution of zeta-isoform did not depend on tissue origin.
- Institute of Endocrinology and Metabolism Ukraine
- National Academy of Sciences of Ukraine Ukraine
- National Academy of Medical Sciences of Ukraine Ukraine
- Academy of Medical Sciences United Kingdom
Hyperplasia, Protein Kinase C-alpha, Blotting, Western, Adrenal Cortex Neoplasms, Isoenzymes, Protein Transport, Cytosol, Microsomes, Adrenal Cortex, Humans, Protein Isoforms, Tissue Distribution, Protein Kinase C, Densitometry
Hyperplasia, Protein Kinase C-alpha, Blotting, Western, Adrenal Cortex Neoplasms, Isoenzymes, Protein Transport, Cytosol, Microsomes, Adrenal Cortex, Humans, Protein Isoforms, Tissue Distribution, Protein Kinase C, Densitometry
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).1 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!