In a previous paper [Trans. Am. Math. Soc. 330, No. 2, 903-915 (1992; Zbl 0759.41009)] the authors have introduced the \(m\)th order cardinal \(B\)-spline-wavelet \(\psi_ m\) and have shown that every function \(f\in L^ 2(-\infty,\infty)\) has a (unique) orthogonal wavelet decomposition \(f=\sum_{k\in\mathbb{Z}}\sum_{j\in\mathbb{Z}}d^ k_ j\psi_ m(2^ k\cdot - j)\). The objective of the present paper is to analyze the wavelet series \(g_ k=\sum_{j\in\mathbb{Z}}d^ k_ j\psi_ m(2^ k\cdot -j)\). More precisely, the authors study the behaviour of the isolated sign changes of \(g_ k\) and, particularly, conditions under which the wavelet series \(g_ k\) is characterized by its isolated sign changes.