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Mammalian Genome
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Mammalian Genome
Article . 1994 . Peer-reviewed
License: Springer TDM
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Mammalian Genome
Article . 1994
Data sources: Europe PubMed Central
Mammalian Genome
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University of Michigan: Deep Blue
Article . 1994
Data sources: Bielefeld Academic Search Engine (BASE)
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Molecular map of Chromosome 19 including three genes affecting bleeding time: ep, ru, and bm

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 1994 United States English Publisher:Springer Science and Business Media LLCJournal:Mammalian Genome, volume 5, pages 356-360 (issn: 0938-8990, eissn: 1432-1777, Copyright policy )
Authors: Novak, E. K.; Keller, Scot A.; O'Brien, E. P.; Guénet, J. -L.; Poirier, C.; Swank, Richard T.;

doi: 10.1007/bf00356554

pmid: 8043950

handle: 2027.42/47011

Molecular map of Chromosome 19 including three genes affecting bleeding time: ep, ru, and bm

Abstract

The mouse ruby eye (ru) and pale ear (ep) pigment dilution genes cause platelet storage pool deficiency (SPD) and prolonged bleeding times. The brachymorphic (bm) gene, in addition to causing skeletal abnormalities, is also associated with prolonged bleeding times. All three hemorrhagic genes are found within 10 cM on Chromosome (Chr) 19. In this study, 15 microsatellite markers and five cDNAs, spanning 21 cM of Chr 19, were mapped in relation to the bm, ep, and ru genes in 457 progeny of an interspecific backcross utilizing the highly inbred strain PWK derived from the Mus musculus musculus species. Several markers were found to be closely linked to the three genes and should be useful as entry points in their eventual molecular identification.

Country
United States
Related Organizations
Keywords

Genetic Markers, Platelet Storage Pool Deficiency, Bleeding Time, Base Sequence, Genotype, Science, Ecology and Evolutionary Biology, Molecular Sequence Data, Life Sciences, Natural Resources and Environment, Molecular, Chromosome Mapping, Mice, Inbred Strains, Cell Biology, Mice, Health Sciences, Animals, Anatomy, Cellular and Developmental Biology, Zoology

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 30
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
30
Average
Top 10%
Top 10%
bronze