
pmid: 15703941
Cleavage of the ring-like cohesin complex by separase triggers segregation of sister chromatids in anaphase. This simplistic model has recently been extended by exciting discoveries on three levels: regulation of anaphase by posttranslational modifications and the cohesin protector shugoshin; non-proteolytic roles of separase; and cohesin-independent linkage of sister chromatids.
Saccharomyces cerevisiae Proteins, SUMO-1 Protein, Cell Cycle Proteins, Saccharomyces cerevisiae, Chromatids, Cytoskeletal Proteins, Endopeptidases, Animals, Humans, Phosphorylation, Anaphase, Biologie, Separase
Saccharomyces cerevisiae Proteins, SUMO-1 Protein, Cell Cycle Proteins, Saccharomyces cerevisiae, Chromatids, Cytoskeletal Proteins, Endopeptidases, Animals, Humans, Phosphorylation, Anaphase, Biologie, Separase
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