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De Novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes

Authors: Hatsune, Chiba; Ryutaro, Hirasawa; Masahiro, Kaneda; Yuko, Amakawa; En, Li; Takashi, Sado; Hiroyuki, Sasaki;

De Novo DNA methylation independent establishment of maternal imprint on X chromosome in mouse oocytes

Abstract

AbstractMouse blastocyst stage embryo stained for histone H3 lysine‐27 trimethylation (red) and DNA (blue). H3K27me3 marks the inactive X chromosome. The study by Chiba et al. in this issue suggests that de novo DNA methyltransferases are dispensable for setting the imprint on the maternally‐derived X chromsome in growing oocytes. See Chiba et al. in this issue.

Keywords

Male, X Chromosome, Lysine, Gene Expression Regulation, Developmental, DNA Methylation, DNA Methyltransferase 3A, Trophoblasts, Histones, Genomic Imprinting, Mice, Blastocyst, Oocytes, Animals, Female, DNA (Cytosine-5-)-Methyltransferases, Transgenes, Alleles

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    popularity
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    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
37
Top 10%
Top 10%
Top 10%
bronze