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Respiratory Medicine
Article
License: Elsevier Non-Commercial
Data sources: UnpayWall
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Respiratory Medicine
Article . 2006
License: Elsevier Non-Commercial
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Respiratory Medicine
Article . 2006 . Peer-reviewed
License: Elsevier Non-Commercial
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Investigating suspected pulmonary embolism during pregnancy

Authors: Dimitrina Petkova; Srikumar Mallick;

Investigating suspected pulmonary embolism during pregnancy

Abstract

Pulmonary embolism (PE) is the commonest cause of maternal death in UK. It is a frequently occurring diagnostic challenge. The false negative and false positive rates for the diagnosis of PE are spectacularly high. Undiagnosed PE has a mortality rate as high as 30%, which falls to 2-8% if the condition is diagnosed and treated appropriately. [Rodger M, Wells PS. Diagnosis of pulmonary embolism. Thromb Res 2001;103:v225-38; Guidelines on Diagnosis and Management of Acute Pulmonary Embolism. Task Force on Pulmonary Embolism, European Society of Cardiology. Eur Heart J 2000;21(16):1301-36]. Physiologic changes of pregnancy further complicate the diagnosis of PE. Although the danger of maternal and foetal death secondary to maternal PE and unnecessary anticoagulation far outweighs the risk of radiation involved in scanning, doctors still hesitate to request appropriate investigation because of concern regarding radiation exposure to the foetus and the absence of any clear, updated guideline. Worried parents need to be counselled appropriately before tests to alleviate anxiety and misunderstanding.

Related Organizations
Keywords

Pulmonary and Respiratory Medicine, Scans, Radiation exposure, Pulmonary embolism, Pregnancy Complications, Cardiovascular, Investigations, Radiation Dosage, Pregnancy, D-dimer, Prenatal Diagnosis, Humans, Female, Pulmonary Embolism, Tomography, X-Ray Computed

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    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    22
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
22
Average
Top 10%
Top 10%
hybrid