Variability of Near-Fainting Responses in Healthy 6–16-Year-old Subjects
Copyright policy )Variability of Near-Fainting Responses in Healthy 6–16-Year-old Subjects
1. Fainting is a common phenomenon in young subjects, but the final events before the actual faint are not well known. The aim of the present study was to study the inter-individual variability of haemodynamic events associated with near-fainting in children and teenagers. 2. Sixty-eight healthy subjects (aged 6–16 years) performed a 70° tilt-up test with intravascular instrumentation for 5 min. Responses in 29 near-fainting subjects were analysed and compared with 39 non-fainting subjects. Arterial pressure was measured by Finapres. Left ventricular stroke volume was computed from the pressure pulsation waveform. 3. Inability to maintain vasomotor tone was the mechanism underlying near-fainting in the vast majority of near-fainting subjects. The three classical haemodynamic responses (vasovagal, vasodepressor and vagal) could be recognized, but large individual differences were found. After tilt back, blood pressure in near-fainters showed a mirror response to the stage before tilt-back; blood pressure gradually increased and was normal at 1 min after tilt-back. 4. The variability in haemodynamic responses on approach of an orthostatic faint is wide in the young.
- Delft University of Technology Netherlands
- Amsterdam UMC Netherlands
- Amsterdam UMC, location AMC Netherlands
- University of Amsterdam Netherlands
Male, Time Factors, Adolescent, Hemodynamics, Blood Pressure, Signal Processing, Computer-Assisted, Stroke Volume, Blood Pressure Monitoring, Ambulatory, Teenagers, Syncope, Electrocardiography, Hypotension, Orthostatic, Hemodynamic Processes, Heart Rate, Tilt-Table Test, Orthostasis, Humans, Female, Vascular Resistance, Cardiac Output, Child, Vasomotor system
Male, Time Factors, Adolescent, Hemodynamics, Blood Pressure, Signal Processing, Computer-Assisted, Stroke Volume, Blood Pressure Monitoring, Ambulatory, Teenagers, Syncope, Electrocardiography, Hypotension, Orthostatic, Hemodynamic Processes, Heart Rate, Tilt-Table Test, Orthostasis, Humans, Female, Vascular Resistance, Cardiac Output, Child, Vasomotor system
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