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Science Signaling
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Science Signaling
Article . 2012 . Peer-reviewed
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Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells

Authors: Eric O. Long; H. Kim; H. Kim;

Complementary Phosphorylation Sites in the Adaptor Protein SLP-76 Promote Synergistic Activation of Natural Killer Cells

Abstract

Targeted tyrosine phosphorylation of an adaptor protein is required for the synergistic activation of natural killer cells by distinct pairs of receptors.

Keywords

Analysis of Variance, Binding Sites, Blotting, Western, Flow Cytometry, Lymphocyte Activation, Phosphoproteins, Models, Biological, Killer Cells, Natural, Interferon-gamma, Antigens, CD, NK Cell Lectin-Like Receptor Subfamily K, Gene Knockdown Techniques, Humans, Immunoprecipitation, RNA Interference, Phosphorylation, Proto-Oncogene Proteins c-vav, Cells, Cultured, Adaptor Proteins, Signal Transducing, DNA Primers

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    66
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
66
Top 10%
Top 10%
Top 10%
bronze