Abstract The S-fold description of Janus-type solutions of type IIB supergravity is investigated. This is done by first studying a U(1) × U (1) invariant sector of the four­ dimensional dyonically-gauged [SO(1) × SO(6)] × ℝ12 maximal supergravity that arises upon reduction of type IIB supergravity on ℝ × S5. Two AdS4 solutions preserving SU(3) and SO (6) gauge symmetry together with $$ \mathcal{N} $$ N = 1 and $$ \mathcal{N} $$ N = 0 supersymmetry are found within this sector. Fetching techniques from the E 7(7) exceptional field theory, these solutions are uplifted to ten-dimensional S-folds of type IIB Janus-type solutions of the form AdS4 × ℝ × M5. The solutions presented here are natural candidates for the holographic duals of three-dimensional $$ \mathcal{N} $$ N = 1 and $$ \mathcal{N} $$ N = 0 interface super-Yang-Mills theories with SU(3) and SU(4) internal symmetry.