Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
Copyright policy )Identification of plasmid IncQ1 and NTEKPC-IId harboring bla KPC-2 in isolates from Klebsiella pneumoniae infections in patients from Recife-PE, Brazil
This study investigated the genetic environment of bla KPC-2 in Klebsiella pnemoniae multi-drug resistant clinical isolates.Four carbapenemase gene isolates resistant to carbapenems, collected from infected patients from two hospitals in Brazil, were investigated using polymerase chain reaction and plasmid DNA sequencing.The bla KPC-2 gene was located between ISKpn6 and a resolvase tnpR in the non-Tn4401 element (NTEKPC-IId). It was detected on a plasmid belonging to the IncQ1 group.To our knowledge, this is the first report of the presence of the bla KPC-2 gene in the NTEKPC-IId element carried by plasmid IncQ1 from infections in Brazil.
- Universidade Federal de Pernambuco Brazil
- Universitas Sisingamangaraja XII Tapanuli Indonesia
- University of Turku Finland
- UNIVERSIDADE DE SAO PAULO Brazil
- Oswaldo Cruz Foundation Brazil
DNA, Bacterial, NTEKPC-IId, Short Communication, Klebsiella pnemoniae, RC955-962, Microbial Sensitivity Tests, Polymerase Chain Reaction, beta-Lactamases, Anti-Bacterial Agents, Klebsiella Infections, Klebsiella pneumoniae, IncQ1, bla KPC-2, Arctic medicine. Tropical medicine, Drug Resistance, Multiple, Bacterial, Humans, Plasmids
DNA, Bacterial, NTEKPC-IId, Short Communication, Klebsiella pnemoniae, RC955-962, Microbial Sensitivity Tests, Polymerase Chain Reaction, beta-Lactamases, Anti-Bacterial Agents, Klebsiella Infections, Klebsiella pneumoniae, IncQ1, bla KPC-2, Arctic medicine. Tropical medicine, Drug Resistance, Multiple, Bacterial, Humans, Plasmids
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