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University of Southern Denmark Research Output
Article . 2003
Data sources: University of Southern Denmark Research Output
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Aquatic Toxicology
Article . 2003 . Peer-reviewed
License: Elsevier TDM
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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Aquatic Toxicology
Article . 2003
Data sources: University of Southern Denmark Research Output
Aquatic Toxicology
Article . 2003
Data sources: Europe PubMed Central
https://dx.doi.org/10.1016/s01...
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Comparative effects and metabolism of two microcystins and nodularin in the brine shrimp Artemia salina

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2003 English Publisher:Elsevier BVJournal:Aquatic Toxicology, volume 62, pages 219-226 (issn: 0166-445X, Copyright policy )
Authors: Beattie, Kenneth A; Ressler, Judith; Wiegand, Claudia; Krause, Eberhard; Codd, Geoffrey A; Steinberg, Christian; Pflugmacher, Stephan;

doi: 10.1016/s0166-445x(02)00091-7

pmid: 12560170

Comparative effects and metabolism of two microcystins and nodularin in the brine shrimp Artemia salina

Abstract

The toxicity and metabolism of the cyanobacterial toxins microcystin-LR (MCLR), Dhb-microcystin-HtyR and nodularin were investigated in the cysts, nauplii and adults of the brine shrimp Artemia salina. The presence of the phase II detoxication system glutathione S-transferase (sGST) in these stages was shown using different substrates. Exposure of adult A. salina to the toxins led to an elevation of GST activity in vivo. All three toxins were conjugated to glutathione via GST, which has been shown as an initial step of microcystin and nodularin detoxication.

Related Organizations
Keywords

Microcystins, Bacterial Toxins, Cyanobacteria, Glutathione, Peptides, Cyclic, Inactivation, Metabolic, Animals, Marine Toxins, Artemia, Enzyme Inhibitors, Glutathione Transferase

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
95
Top 10%
Top 10%
Top 10%
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