Mutations in the cardiac Troponin C gene are a cause of idiopathic dilated cardiomyopathy in childhood
Copyright policy )Mutations in the cardiac Troponin C gene are a cause of idiopathic dilated cardiomyopathy in childhood
Abstract The role of familial disease in childhood dilated cardiomyopathy is unknown. A novel mutation in the cardiac Troponin C gene has been identified recently in a family with dilated cardiomyopathy. Here we present a subsequent case of dilated cardiomyopathy occurring in a child from the same family, and emphasise the implications for future screening and counselling.
- University College Hospital at Westmoreland Street United Kingdom
- University College London United Kingdom
- University College London Hospitals NHS Foundation Trust United Kingdom
- Great Ormond Street Hospital Children's Charity United Kingdom
Cardiomyopathy, Dilated, Male, Biopsy, Myocardium, DNA Mutational Analysis, DNA, Myocardial Contraction, Severity of Illness Index, Echocardiography, Doppler, Color, Pedigree, Electrocardiography, Child, Preschool, Mutation, Heart Transplantation, Humans, Genetic Predisposition to Disease, Troponin C, Follow-Up Studies
Cardiomyopathy, Dilated, Male, Biopsy, Myocardium, DNA Mutational Analysis, DNA, Myocardial Contraction, Severity of Illness Index, Echocardiography, Doppler, Color, Pedigree, Electrocardiography, Child, Preschool, Mutation, Heart Transplantation, Humans, Genetic Predisposition to Disease, Troponin C, Follow-Up Studies
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).21 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10%
Citations provided by BIP!Popularity provided by BIP!