An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure
Copyright policy )An Orally Active TRPV4 Channel Blocker Prevents and Resolves Pulmonary Edema Induced by Heart Failure
Transient receptor potential vanilloid 4 (TRPV4) channels are expressed in human heart failure lungs, which can be blocked to prevent and resolve heart failure–induced pulmonary edema.
- Cellzome, GSK, Middlesex, UK.
- GlaxoSmithKline (United States) United States
- University of South Alabama United States
Heart Failure, Mice, Knockout, Administration, Oral, Blood Pressure, Pulmonary Edema, In Vitro Techniques, Permeability, Rats, Disease Models, Animal, Mice, Protein Transport, Heart Rate, Membrane Transport Modulators, Animals, Humans, Calcium, Endothelium, Diuretics, Ion Channel Gating, Lung
Heart Failure, Mice, Knockout, Administration, Oral, Blood Pressure, Pulmonary Edema, In Vitro Techniques, Permeability, Rats, Disease Models, Animal, Mice, Protein Transport, Heart Rate, Membrane Transport Modulators, Animals, Humans, Calcium, Endothelium, Diuretics, Ion Channel Gating, Lung
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