Design of small molecules targeting RNA structure from sequence
Copyright policy )NIH| Understanding Epstein Barr virus oncogenicity through non-coding RNA structure ,
NIH| Chemical approaches for precise recognition of a toxic RNA repeat ,
NIH| Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biology ,
NIH| Sequence-based Design of Small Molecules Targeting RNA ,
NIH| Finding, folding and characterizing the functions of disease-relevant RNA structures ,
NIH| Targeted degradation of RNAs by using small molecules
Andrei Ursu; Jessica L. Childs-Disney; Ryan J. Andrews; Collin A. O’Leary; Samantha M. Meyer; Alicia J. Angelbello; Walter N. Moss; +1 Authors
Andrei Ursu; Jessica L. Childs-Disney; Ryan J. Andrews; Collin A. O’Leary; Samantha M. Meyer; Alicia J. Angelbello; Walter N. Moss; Matthew D. Disney;
Design of small molecules targeting RNA structure from sequence
Herein, we describe methods to identify structured regions within disease-causing RNAs and to design lead small molecules that selectively bind these structures to modulate function.
- IOWA STATE UNIVERSITY
- IOWA STATE UNIVERSITY
- Iowa State University United States
- Department of Chemistry The Scripps Research Institute United States
- Scripps Research Institute United States
Small Molecule Libraries, MicroRNAs, Huntington Disease, Drug Design, Antagomirs, Nucleic Acid Conformation, RNA, RNA, Viral
Small Molecule Libraries, MicroRNAs, Huntington Disease, Drug Design, Antagomirs, Nucleic Acid Conformation, RNA, RNA, Viral
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selected citations
Citations provided by BIP!
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 41
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NIH| Understanding Epstein Barr virus oncogenicity through non-coding RNA structure, NIH| Chemical approaches for precise recognition of a toxic RNA repeat, NIH| Design of precision small molecules targeting RNA repeating transcripts to manipulate and study disease biology, NIH| Sequence-based Design of Small Molecules Targeting RNA
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