
pmid: 925035
The 5'-terminal sequences of VA-RNA I produced in cells infected with adenovirus 2 were analyzed. The RNA contained a mixture of mono-, di-, and triphosphate ends. The largest part of the RNA has 5'-terminal mono-, di-, or triphosphoguanylic acid, but a portion of the RNA has a 5'-terminal mono-, di-, or triphosphoadenylic acid. An RNA with 5'-terminal adenylic acid was purified and gave the same oligonucleotide map as the major form of VA-RNA I, except for the 5'-terminal products. We therefore conclude that transcription of VA-RNA I can initiate at two different nearby sites.
Oligoribonucleotides, Base Sequence, Transcription, Genetic, Adenine Nucleotides, RNA, Viral, Guanine Nucleotides, Adenoviridae
Oligoribonucleotides, Base Sequence, Transcription, Genetic, Adenine Nucleotides, RNA, Viral, Guanine Nucleotides, Adenoviridae
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