Mapping of the mouse bilirubin UDP-glucuronosyltransferase gene (Gnt-1) to chromosome 1 by restriction fragment length variations
Copyright policy )Mapping of the mouse bilirubin UDP-glucuronosyltransferase gene (Gnt-1) to chromosome 1 by restriction fragment length variations
Restriction endonuclease fragment length variations (RFLVs) were detected by using a rat cDNA probe for the bilirubin UDP-glucuronosyltransferase (UDPGT) gene between two mouse strains, 129/Sv and MOL-MIT. RFLVs of the gene were found by EcoRI and PvuII digestions. From linkage analyses of the three-point cross test using Elo and En-1 as marker genes, the bilirubin UDPGT gene was mapped at position 37 on chromosome 1. Bilirubin and phenol UDPGTs have been suggested to be expressed by a single gene by alternative splicing in human and rat. The mouse bilirubin UDPGT gene was named Gnt-1.
Mice, Inbred C57BL, Mice, Animals, Chromosome Mapping, Bilirubin, Glucuronosyltransferase, Crosses, Genetic, Polymorphism, Restriction Fragment Length
Mice, Inbred C57BL, Mice, Animals, Chromosome Mapping, Bilirubin, Glucuronosyltransferase, Crosses, Genetic, Polymorphism, Restriction Fragment Length
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