To control micro-organisms in bio-systems, a holographic model is proposed. In this proposal, virtual micro-molecules could be produced through two ways. In first method, a macro-light source with the shape of a micro-organism could be built. This source emits some waves which collide with lenses of a microscope, return and induce micro-image of desired object. Microbes interact with this image as a real micro-molecule. One can test this idea by using a multi-gonal lamp and a microscope. It is observed that the shape of lamp is induced in any micro-bubble.In second method, using two light sources for a microscope in a dark lab, two waves with different colors are emerged. Light waves take shape of microbes, collide with lenses, return and produce virtual microbes. These microbes could deceive real bacteria and micro-organisms and control them. Using these techniques, some infectious diseases could be cured.