Enhancement of Stress Tolerance inSaccharomyces cerevisiaeby Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes
Copyright policy )Enhancement of Stress Tolerance inSaccharomyces cerevisiaeby Overexpression of Ubiquitin Ligase Rsp5 and Ubiquitin-Conjugating Enzymes
Yeast Saccharomyces cerevisiae cells overexpressing essential ubiquitin ligase Rsp5 or ubiquitin-conjugating enzymes (Ubc1-Ubc13) showed tolerance to various stresses. Co-overexpression of Rsp5 and Ubc1, Ubc2, Ubc3, Ubc5, Ubc6, Ubc9, Ubc10, Ubc11, Ubc12, or Ubc13 further enhanced stress tolerance. These results suggest that overexpression of ubiquitin-related enzymes might be a useful method for breeding novel stress-resistant strains.
Saccharomyces cerevisiae Proteins, Endosomal Sorting Complexes Required for Transport, Gene Expression Regulation, Fungal, Ubiquitin-Conjugating Enzymes, Ubiquitin-Protein Ligase Complexes, Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins, Endosomal Sorting Complexes Required for Transport, Gene Expression Regulation, Fungal, Ubiquitin-Conjugating Enzymes, Ubiquitin-Protein Ligase Complexes, Saccharomyces cerevisiae
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