Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells
Copyright policy )Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 M pro /3CL pro in Living Cells
The main protease, M pro , of SARS-CoV-2 is an essential viral protein required for the earliest steps of infection. It is therefore an attractive target for antiviral drug development.
- Howard Hughes Medical Institute United States
- University of Minnesota Morris United States
- Masonic Cancer Center United States
- Baylor College of Medicine United States
- Texas Medical Center United States
570, Medical Sciences, Epidemiology, Respiratory Tract Diseases, Biophysics, coronavirus, 610, Diseases, Biochemistry, Microbiology, Antiviral Agents, main protease (Mpro/3CLpro), Luciferases, Firefly, Medical Specialties, Medicine and Health Sciences, Clinical Epidemiology, Protease Inhibitors, gain-of-signal cell-based systems, Amino Acids, Luciferases, Firefly, Biology, Coronavirus 3C Proteases, SARS-CoV-2 (SARS2), SARS-CoV-2, COVID-19, Life Sciences, Community Health and Preventive Medicine, QR1-502, viral protease inhibitors, Virus Diseases, SARS-CoV-2/, and Structural Biology, Public Health, Research Article
570, Medical Sciences, Epidemiology, Respiratory Tract Diseases, Biophysics, coronavirus, 610, Diseases, Biochemistry, Microbiology, Antiviral Agents, main protease (Mpro/3CLpro), Luciferases, Firefly, Medical Specialties, Medicine and Health Sciences, Clinical Epidemiology, Protease Inhibitors, gain-of-signal cell-based systems, Amino Acids, Luciferases, Firefly, Biology, Coronavirus 3C Proteases, SARS-CoV-2 (SARS2), SARS-CoV-2, COVID-19, Life Sciences, Community Health and Preventive Medicine, QR1-502, viral protease inhibitors, Virus Diseases, SARS-CoV-2/, and Structural Biology, Public Health, Research Article
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