Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
Copyright policy ) Brian L. Yaspan; David F. Williams; Frank G. Holz; Carl D. Regillo; Zhengrong Li; Amy Dressen; Menno van Lookeren Campagne; +9 Authors
Brian L. Yaspan; David F. Williams; Frank G. Holz; Carl D. Regillo; Zhengrong Li; Amy Dressen; Menno van Lookeren Campagne; Kha N. Le; Robert R. Graham; Tatiana Beres; Tushar R. Bhangale; Lee A. Honigberg; Ashley Smith; Erin C. Henry; Carole Ho; Erich C. Strauss;
Targeting factor D of the alternative complement pathway reduces geographic atrophy progression secondary to age-related macular degeneration
The phase 2 MAHALO clinical trial shows that lampalizumab reduces geographic atrophy secondary to age-related macular degeneration and implicates complement dysregulation in disease pathogenesis.
- GENENTECH INC United States
- University of Bonn Germany
- Wills Eye Hospital United States
Male, Complement Pathway, Alternative, Middle Aged, Immunoglobulin Fab Fragments, Macular Degeneration, Geographic Atrophy, Disease Progression, Humans, Complement Factor D, Female, Aged
Male, Complement Pathway, Alternative, Middle Aged, Immunoglobulin Fab Fragments, Macular Degeneration, Geographic Atrophy, Disease Progression, Humans, Complement Factor D, Female, Aged
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP! 174
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