Survivin over-expression is correlated with a poor prognosis in esophageal cancer patients
Copyright policy )Survivin over-expression is correlated with a poor prognosis in esophageal cancer patients
The prognostic role of survivin in esophageal cancer (EC) remains controversial. This meta-analysis aimed to clarify the association of survivin with survival in EC patients.Relevant studies published up to November 2014 were identified using PubMed and Embase. Only studies in which survivin was detected through immunohistochemical staining were included. STATA 12.0 was used in this meta-analysis.A total of 9 studies, which comprised 610 patients, were included in the meta-analysis. The combined hazard ratio (HR) of 1.76 (95% CI, 1.40-2.21; P0.05).Survivin overexpression is associated with poor prognosis in EC patients.
- Soochow University China (People's Republic of)
- First Affiliated Hospital of Soochow University China (People's Republic of)
Gene Expression Regulation, Neoplastic, Survival Rate, Esophageal Neoplasms, Survivin, Biomarkers, Tumor, Carcinoma, Squamous Cell, Humans, Esophageal Squamous Cell Carcinoma, Prognosis, Inhibitor of Apoptosis Proteins
Gene Expression Regulation, Neoplastic, Survival Rate, Esophageal Neoplasms, Survivin, Biomarkers, Tumor, Carcinoma, Squamous Cell, Humans, Esophageal Squamous Cell Carcinoma, Prognosis, Inhibitor of Apoptosis Proteins
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