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Accuracy of the VITEK 2 System To Detect Glycopeptide Resistance in Enterococci

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2001 Netherlands Publisher:American Society for MicrobiologyJournal:Journal of Clinical Microbiology, volume 39, pages 351-353 (issn: 0095-1137, eissn: 1098-660X,

Authors: Nicole van den Braak; Henri A. Verbrugh; Alex van Belkum; Wil H. F. Goessens; Hubert P. Endtz;

doi: 10.1128/jcm.39.1.351-353.2001

pmid: 11136798

pmc: PMC87729

Accuracy of the VITEK 2 System To Detect Glycopeptide Resistance in Enterococci

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Abstract

ABSTRACT We evaluated the accuracy of the VITEK 2 fully automated system to detect and identify glycopeptide-resistant enterococci (GRE) compared to a reference agar dilution method. The sensitivity of vancomycin susceptibility testing with VITEK 2 for the detection of vanA , vanB , and vanC1 strains was 100%. The sensitivity of vancomycin susceptibility testing of vanC2 strains was 77%. The sensitivity of teicoplanin susceptibility testing of vanA strains was 90%. Of 80 vanC enterococci, 78 (98%) were correctly identified by VITEK 2 as Enterococcus gallinarum/Enterococcus casseliflavus . Since the identification and susceptibility data are produced within 3 and 8 h, respectively, VITEK 2 appears a fast and reliable method for detection of GRE in microbiology laboratories.

Country

Netherlands

Related Organizations

Erasmus University Rotterdam
Netherlands
Erasmus University Medical Center
Netherlands

Keywords

Drug Resistance, Microbial, Vancomycin Resistance, Microbial Sensitivity Tests, EMC MM-04-28-01, Sensitivity and Specificity, Anti-Bacterial Agents, Bacterial Proteins, Transferases, Vancomycin, Humans, Teicoplanin, Enterococcus, Gram-Positive Bacterial Infections

1 Research products, page 1 of 1

Detection and Differentiation of vanC-1 , vanC-2 , and vanC-3 Glycopeptide Resistance Genes in Enterococci
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