
pmid: 20472378
We describe a 17-year-old Caucasian adolescent with ulcerative colitis who presented with cerebral venous sinus thrombosis. Laboratory investigation revealed low protein S levels. With successful management the patient remained without neurologic sequalae. Although there may be an association between ulcerative colitis and cerebral venous sinus thrombosis, the exact pathophysiologic mechanism remains unknown.
Male, Venous Thrombosis, Protein S/metabolism, Adolescent, Warfarin/therapeutic use, Anticoagulants, Colitis, Ulcerative/pathology/*physiopathology, Venous Thrombosis/drug therapy/*pathology/physiopathology, Magnetic Resonance Imaging, Protein S, Anticoagulants/therapeutic use, Intracranial Thrombosis/drug therapy/*pathology/physiopathology, Humans, Colitis, Ulcerative, Warfarin, Intracranial Thrombosis
Male, Venous Thrombosis, Protein S/metabolism, Adolescent, Warfarin/therapeutic use, Anticoagulants, Colitis, Ulcerative/pathology/*physiopathology, Venous Thrombosis/drug therapy/*pathology/physiopathology, Magnetic Resonance Imaging, Protein S, Anticoagulants/therapeutic use, Intracranial Thrombosis/drug therapy/*pathology/physiopathology, Humans, Colitis, Ulcerative, Warfarin, Intracranial Thrombosis
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