A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
Copyright policy )A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
We performed a genome-wide association study of 19,779 nonsynonymous SNPs in 735 individuals with Crohn disease and 368 controls. A total of 7,159 of these SNPs were informative. We followed up on all 72 SNPs with P 0.4), these data suggest that the underlying biological process may be specific to Crohn disease.
- Kings College London, University of London United Kingdom
- King's College London United Kingdom
- University Hospital Schleswig-Holstein Germany
- Max Planck Institute for Informatics Germany
- Kiel University Germany
Models, Molecular, Molecular Sequence Data, Nod2 Signaling Adaptor Protein, 610, Autophagy-Related Proteins, Polymorphism, Single Nucleotide, 618, Crohn Disease, Humans, Genetic Predisposition to Disease, Carrier Proteins
Models, Molecular, Molecular Sequence Data, Nod2 Signaling Adaptor Protein, 610, Autophagy-Related Proteins, Polymorphism, Single Nucleotide, 618, Crohn Disease, Humans, Genetic Predisposition to Disease, Carrier Proteins
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