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An overview of Cdk1-controlled targets and processes

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 01 Jan 2010 United States English Publisher:Springer Science and Business Media LLCJournal:Cell Division, volume 5, page 11 (issn: 1747-1028, Copyright policy )
Authors: Enserink, Jorrit M; Kolodner, Richard D;

doi: 10.1186/1747-1028-5-11

pmid: 20465793

pmc: PMC2876151

An overview of Cdk1-controlled targets and processes

Abstract

The cyclin dependent kinase Cdk1 controls the cell cycle, which is best understood in the model organism S. cerevisiae. Research performed during the past decade has significantly improved our understanding of the molecular machinery of the cell cycle. Approximately 75 targets of Cdk1 have been identified that control critical cell cycle events, such as DNA replication and segregation, transcriptional programs and cell morphogenesis. In this review we discuss currently known targets of Cdk1 in the budding yeast S. cerevisiae and highlight the role of Cdk1 in several crucial processes including maintenance of genome stability.

Country
United States
Related Organizations
Keywords

QH573-671, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Cell Biology, Review, Cytology, Biochemistry, RC254-282

  • BIP!
    Impact byBIP!
    citations
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 363
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 1%
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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
363
Top 1%
Top 1%
Top 1%
Green
gold
Related to Research communities
Cancer Research