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Team Effort by TRAPP Forces a Nucleotide Fumble

descriptionPublicationkeyboard_double_arrow_right Article 01 Jun 2008 English Publisher:Elsevier BVJournal:Cell, volume 133, pages 1,141-1,143 (issn: 0092-8674, Copyright policy )
Authors: Suzanne R. Pfeffer; Ryan M. Nottingham;

doi: 10.1016/j.cell.2008.06.012

pmid: 18585348

Team Effort by TRAPP Forces a Nucleotide Fumble

Abstract

TRAPPI is a multisubunit protein complex on the Golgi that activates the small GTPase Ypt1p to facilitate the receipt of transport vesicles inbound from the endoplasmic reticulum. Cai et al. (2008) now present structural and biochemical analyses of yeast TRAPPI in a complex with Ypt1p revealing a unique mechanism by which TRAPPI catalyzes guanine nucleotide exchange.

Related Organizations
Keywords

Protein Transport, Saccharomyces cerevisiae Proteins, Biochemistry, Genetics and Molecular Biology(all), rab GTP-Binding Proteins, Vesicular Transport Proteins, Golgi Apparatus, Guanine Nucleotide Exchange Factors, Saccharomyces cerevisiae, Guanine Nucleotides

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
hybrid