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Additional file 2: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

Name: Additional file 2: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model
Keywords: 3. Good health

descriptionPublicationkeyboard_double_arrow_right Other literature type 01 Jan 2019Publisher:figshare

Authors: Benedetto, Giulia Di; Burgaletto, Chiara; Carta, Anna; Saccone, Salvatore; Lempereur, Laurence; Mulas, Giovanna; Loreto, Carla; +2 Authors

doi: 10.6084/m9.figshare.9599939.v1 , 10.6084/m9.figshare.9599939

Additional file 2: of Beneficial effects of curtailing immune susceptibility in an Alzheimerâ s disease model

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Abstract

Figure S2. Effects of the treatment with an anti-TNFSF10 monoclonal antibody on the expression of FoxP3, as well as the anti-inflammatory protein IL-10 in the hippocampus of 3xTg-AD mice. Immunofluorescence by confocal microscopy of hippocampi for IL-10 and FoxP3 expression and co-localization from the same animal groups as above (merge column; DAPIâ =â nuclear staining). WT: wild type animals; AD: 3xTg-AD animals; veh: vehicle. Negative controls are reported in all panels marked with acronyms of secondary antibodies labeled with, respectively, Texas Red (TR) and Fluorescineisothiocyanate (FITC). (PDF 428 kb)

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