‘A characteristic feeling is that from older anxietas tibiarum: a strange but descriptive compulsion to move has invaded the legs of the infl icted person. Every moment sees the legs brought into a different position; drawn up, stretched out, abducted, spread apart and crossed over one another. However, these movements are not sudden or violent, rather they are slow, mindful as if it were of eventually fi nding the one position that will give the most relief. In every strange description of the nervous tension of hysteria one often also fi nds this train of involuntary agitation displayed in the legs and feet. The same thing also occurs however elsewhere without Restless leg syndrome is characterised by: (1) a ‘compulsive’ restlessness or need to move the legs, often associated with paraesthesiae or dysaesthesiae, (2) symptoms at rest or disturbing sleep, quickly but temporarily relieved by standing and walking, (3) nocturnal worsening of symptoms. Additionally, 75% of patients also experience periodic limb movement disorder characterized by involuntary leg twitching or jerking movements during sleep, which typically occur every 10–60 s throughout the night. Thomas Willis [1] described the syndrome in 1672, and in the 1685 edition of his textbook wrote,