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ESTUDIO DE LA REACCIÓN DE AZA DIELS-ALDER SOBRE DIENOS CONJUGADOS HALOGENADOS

Authors: García-Uceda, Rafael; Roldan-Molina, Esther; Navarro, Jorge A. R.; Oltra, J. Enrique;

ESTUDIO DE LA REACCIÓN DE AZA DIELS-ALDER SOBRE DIENOS CONJUGADOS HALOGENADOS

Abstract

{"references": ["[1]\tDiels, O.; Alder, K. Synthesen in der hydroaromatischen Reihe. Justus Liebigs Ann. Chem. 1928, 460, 98-122", "[2]\tAlrededor de 2000 referencias en Sci FInder incluyen la Diels-Alder en la s\u00edntesis de productos naturales. Algunos reviews revelantes son: a) Nicolaou, K.C.; Snyder, S.A.; Montagnon, T.; Vassilikogiannakis, G. The Diels-Alder Reaction in Total Synthesis. Angew, Chem. Int. Ed. 2002, 41, 1668- 1698; b) Takao, K.; Munakata, R.; Tadano, K. Recent Advances in Natural Product Synthesis by Using Intramolecular Diels-Alder Reactions. Chem. Rev. 2005, 105, 4779-4807; c) Gregoritza, M.; Brandl, F.P. The Diels-Alder Reaction: A Powerful Tool for the Design of Drugs Delivery Systems and Biomaterials. Eur. J. Pharm. Biopharm. 2015, 97, 438- 453; d) Yang, B.; Gao, S. Recent advances in the application of Diels\u2013Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis. Chem. Soc. Rev. 2018, 47, 7926-7953.", "[3]\tRoldan-Molina, E.; Nievas, M.M.; Navarro, J.A.R.; Oltra, J.E. CpTiCl2\u2010Catalyzed Cross\u2010Coupling between Internal Alkynes and Ketones: a Novel Concept in the Synthesis of Halogenated, Conjugated Dienes. Chem. Eur. J. 2020, 26, 8296\u20138301.", "[4]\tG. Uceda, R.; Roldan-Molina, E.; Navarro, J.A.R.; Oltra, J.E. The Aza Diels-Alder Reaction on Brominated Conjugated Dienes. Eur. J. Org. Chem. 2021, 2003\u20132005."]}

Los autores agradecen a la Junta de Andalucía por la concesión del proyecto P18-RT-612. Esther Roldán-Molina agradece a la Universidad de Granada (UGR) su contrato de investigación posdoctoral. Rafael García-Uceda agradece a la Universidad de Granada (UGR) la concesión de su beca de Inicio a la Investigación.

Resumen de la publicación de una participación en formato µVídeo en en el congreso Divulga NextGen (1ª edición) que se celebrará online, de manera gratuita y en las redes sociales los días 26, 27 y 28 de mayo de 2021.

Keywords

síntesis orgánica, Diels-Alder, PTAD, dienos halogenados

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