Correlation of Depth of Anesthesia Indexes with MAC in Volatile Anesthesia
Correlation of Depth of Anesthesia Indexes with MAC in Volatile Anesthesia
The aim of this study is to investigate the effectiveness of the commercial EEG-based indexes (BIS, SE/RE, AEP) and the sample entropy measure in assessing the depth of anesthesia in case of different agents (isoflurane, desflurane and sevoflurane) and induction protocols (propofol, VIMA, VCRII). The relationships between the indexes and the anesthetic concentration were quantified in 82 orthopedic patients using the linear Pearsons correlation coefficient and the Spearman’s rank correlation coefficient. The highest Spearman’s rank correlation coefficient was observed for the SE in sevoflurane, and for RE in isoflurane and desflurane anesthesia. If the linear Pearson’s correlation coefficient is considered, BIS gives better correlation in isoflurane and desflurane, and SE in sevoflurane anesthesia.
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