Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes
Copyright policy )Glial fibrillary acidic protein: The component of iintermediate filaments in the vertebrate brain astrocytes
Glial fibrillary acidic protein (GFAP) refers to the type III intermediate filament proteins and is the essential component of the cytoskeleton in astrocytes of all vertebrates. This review presents current data on the molecular organization of GFAP in a comparative aspect. The results of most relevant studies using immunocytochemical labeling of the protein are summarized. The data on the changes in expression of GFAP in Alexander disease caused by the primary pathology of astrocytes are presented.
- Department of Medical Sciences Russian Federation
- Institute of Experimental Medicine Russian Federation
- Russian Academy of Sciences Russian Federation
- Russian Academy
Gene Expression Regulation, Astrocytes, Glial Fibrillary Acidic Protein, Intermediate Filaments, Animals, Brain, Humans, Alexander Disease
Gene Expression Regulation, Astrocytes, Glial Fibrillary Acidic Protein, Intermediate Filaments, Animals, Brain, Humans, Alexander Disease
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