Building Complexity: Making and Breaking Synthetic Subunits of the HIV Capsid

descriptionPublicationkeyboard_double_arrow_right Article 01 Aug 2019 English Publisher:Elsevier BVJournal:Cell Host & Microbe, volume 26, pages 151-153 (issn: 1931-3128,

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Authors: Leo C, James; Till, Böcking;

doi: 10.1016/j.chom.2019.07.011

pmid: 31415744

Building Complexity: Making and Breaking Synthetic Subunits of the HIV Capsid

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Abstract

In this issue of Cell Host & Microbe, Summers et al. (2019) use protein engineering to generate a toolbox of HIV-1 capsid oligomers. In an accompanying Cell Reports paper, Huang et al. (2019) use these oligomers to determine how the capsid engages the kinesin-1 adaptor protein FEZ1.

Related Organizations

UNSW Sydney
Australia
MRC Laboratory of Molecular Biology
United Kingdom
Medical Research Council
United Kingdom

Keywords

Capsid, HIV-1, Kinesins, Capsid Proteins, Adaptor Proteins, Signal Transducing

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