Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome
Copyright policy )Effect of ibrutinib treatment on hemolytic anemia and acrocyanosis in cold agglutinin disease/cold agglutinin syndrome
Cold antibody-mediated autoimmune hemolytic anemia (cAIHA) is a rare disease, usually related to an underlying indolent clonal B-cell lymphoproliferative disorder. Jalink and colleagues describe an international retrospective analysis of Bruton tyrosine kinase (BTK) inhibition in patients with cAIHA. The data indicate a rapid and notable improvement in both the hemolytic anemia as well as acrocyanosis, suggesting that this may be an effective approach, regardless of underlying pathology or MYD88 mutational status.
- Harvard University United States
- Leiden University Medical Center Netherlands
- National and Kapodistrian University of Athens (NTUA Greece
- University of Amsterdam Netherlands
- Amsterdam UMC Netherlands
Aged, 80 and over, Cyanosis, Male, Adenine, Middle Aged, Piperidines, Agammaglobulinaemia Tyrosine Kinase, Humans, Female, Anemia, Hemolytic, Autoimmune, Protein Kinase Inhibitors, Aged, Retrospective Studies
Aged, 80 and over, Cyanosis, Male, Adenine, Middle Aged, Piperidines, Agammaglobulinaemia Tyrosine Kinase, Humans, Female, Anemia, Hemolytic, Autoimmune, Protein Kinase Inhibitors, Aged, Retrospective Studies
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