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Structure of the ubiquitin-encoding genes of cryptococcus neoformans

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1995 English Publisher:Elsevier BVJournal:Gene, volume 161, pages 113-117 (issn: 0378-1119,

Authors: Eric D. Spitzer; Silvia Spitzer;

doi: 10.1016/0378-1119(95)00231-t

pmid: 7642124

Structure of the ubiquitin-encoding genes of cryptococcus neoformans

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Abstract

Cryptococcus neoformans (Cn) contains two ubiquitin (UBI)-encoding genes located on separate chromosomes. The UBI1 gene consists of UBI fused to a 53-amino-acid (aa) tail and is 95% identical to the Saccharomyces cerevisiae (Sc) UBI1 which codes for an UBI-CEP52 ribosomal protein fusion. UBI4 is a polyubiquitin gene that contains five UBI repeats. The UBI4 aa sequences differ from Sc UBI by a single aa. UBI1 contains two introns in the UBI-encoding portion and two introns in the tail. Single introns are present in three of the repeats in UB14 and are located at the same positions as those in UBII. There was also an average of 15% nt differences among UBI repeats. The results provide evidence of extensive recombination and/or conversion events between repeated genes in Cn.

Related Organizations

Stony Brook University
United States

Keywords

Base Sequence, Sequence Homology, Amino Acid, Genes, Fungal, Molecular Sequence Data, Cryptococcus neoformans, DNA, Recombinant, Amino Acid Sequence, Ubiquitins, Introns

8 Research products, page 1 of 1

Filobasidiella neoformans polyubiquitin (CNUBI4) gene, complete cds.
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Polyubiquitin
2017IsRelatedTo
Cryptococcus neoformans ubiquitin-carboxy extension protein fusion
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Cryptococcus neoformans polyubiquitin
2018IsRelatedTo
Filobasidiella neoformans ubiquitin-carboxy extension protein fusion,complete cds.
2018IsRelatedTo
Polyubiquitin
2017IsRelatedTo
Ubiquitin-60S ribosomal protein L40
2017IsRelatedTo
Ubiquitin-60S ribosomal protein L40
2017IsRelatedTo

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