Formamicin, a Novel Antifungal Antibiotic Produced by a Strain of Saccharothrix sp. I. Taxonomy, Production, Isolation and Biological Properties.
Copyright policy )Formamicin, a Novel Antifungal Antibiotic Produced by a Strain of Saccharothrix sp. I. Taxonomy, Production, Isolation and Biological Properties.
Formamicin, an antifungal antibiotic, was isolated from the cultured broth of an actinomycete strain. The strain was isolated from a soil collected at Setagaya-ku, Tokyo, Japan, and identified as Saccharothrix sp. MK27-91F2. Formamicin was extracted with acetone from cultured mycelia and purified by silicagel and Sephadex LH-20 column chromatographies and CPC (Centrifugal liquid-liquid Partition Chromatography). Formamicin showed strong antimicrobial activity against phytopathogenic fungi.
Antibiotics, Antineoplastic, Antifungal Agents, Fungi, Microbial Sensitivity Tests, Anti-Bacterial Agents, Mice, Actinomycetales, Tumor Cells, Cultured, Animals, Humans, Macrolides
Antibiotics, Antineoplastic, Antifungal Agents, Fungi, Microbial Sensitivity Tests, Anti-Bacterial Agents, Mice, Actinomycetales, Tumor Cells, Cultured, Animals, Humans, Macrolides
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