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Immunity
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Immunity
Article . 2018 . Peer-reviewed
License: Elsevier Non-Commercial
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https://pubmed.ncbi.nlm.nih.go...
Article . 2019
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https://dx.doi.org/10.1016/j.i...
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HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis

descriptionPublicationkeyboard_double_arrow_right Article 01 Oct 2018 English Publisher:Elsevier BVJournal:Immunity, volume 49, pages 582-584 (issn: 1074-7613, Copyright policy )
Authors: Ho Min, Kim; You-Me, Kim;

doi: 10.1016/j.immuni.2018.09.021

pmid: 30332623

HMGB1: LPS Delivery Vehicle for Caspase-11-Mediated Pyroptosis

Abstract

Recognition of cytoplasmic lipopolysaccharide (LPS) by caspase-11 leads to pyroptosis and secretion of inflammatory mediators. In this issue of Immunity, Deng et al. (2018) report that high-mobility group box 1 (HMGB1) secreted by hepatocytes delivers extracellular LPS into the cytoplasm and mediates pyroptosis.

Related Organizations
Keywords

Endotoxins, Lipopolysaccharides, Caspases, Sepsis, Pyroptosis, Humans, HMGB1 Protein

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
51
Top 10%
Top 10%
Top 10%
hybrid
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