What are we to do for the relief of our young women patients who suffer persistently from menstrual pain and spasm? I allude to those cases which have resisted all approved drug medication, including alimentary correctives and eliminants, as well as antispasmodics, and whose life is clouded during one-fourth of each month by an ever-increasing degree of morphia stupefaction as the only relief from intense pain. The pathology of cases of this nature is usually of a dual character. There is commonly a chronic inflammatory process present in the endometrium, accompanied by congestive conditions in the ovary, the endometritis being merely catarrhal, and there is also a most pronounced erethism of the pelvic neuromuscular apparatus. This neuromuscular erethism is the feature wherein these cases differ so greatly from those of mere endometritis in parous women, unaccompanied by the menorrhalgic spasms. The pain and spasm are probably present in the younger