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Bratislava Medical Journal
Article . 2014 . Peer-reviewed
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Primary hyperparathyreosis: Is concordant sonography and scintigraphy really so important?

Authors: M, Gergel; I, Brychta; M, Vician; J, Olejnik;

Primary hyperparathyreosis: Is concordant sonography and scintigraphy really so important?

Abstract

In primary hyperparathyreosis, US and scintigraphy are the most usual preoperative localization methods for detection of parathyroid adenomas or hyperplasia.88 (80 female) patients were detected. Unilateral neck exploration was performed in 43 patients (48.9 %) and bilateral exploration in 45 patients (51.1 %). The cure rate was 97.6 %. None case of parathyroid hyperplasia was detected, there were 2 cases of duplex adenoma. For left/right and quadrant localization, sensitivity of US was 71.05 % and 55.07 %, of scintigraphy 95.77 % and 88.71 %, and in concordant imaging 97.67 % and 96.77 %. Analogically, PPV was: US 91.53 % and 76.00 %, scintigraphy 87.18 % and 74.32 %, concordant imaging 93.33 %and 81.08 %. Only US sensitivity was significantly lower, all other differences showed no statistical significance.Our data showed low sensitivity but a high positive predictive value of ultrasonography and a high diagnostic value of scintigraphy. Sensitivity and the positive predictive value of concordant localization showed no significant difference, compared to scintigraphy. The routine need for concordance for parathyroid adenoma localization appears dubious, however, its value for prediction of multiglandular disease remains important for protocols that do not apply peroperative localization (Tab. 2, Ref. 35).

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Keywords

Adult, Aged, 80 and over, Male, Middle Aged, Hyperparathyroidism, Primary, Parathyroid Glands, Parathyroid Neoplasms, Preoperative Care, Humans, Female, Aged, Retrospective Studies, Tomography, Emission-Computed, Ultrasonography

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Average
Average
Average
gold