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Mammalian Genome
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Mammalian Genome
Article . 1996 . Peer-reviewed
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Mammalian Genome
Article . 1996
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https://dx.doi.org/10.1007/s00...
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Genetic mapping of the human and mouse phospholipase C genes

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1996 English Publisher:Springer Science and Business Media LLCJournal:Mammalian Genome, volume 7, pages 501-504 (issn: 0938-8990, eissn: 1432-1777, Copyright policy )
Authors: M S, Lyu; D J, Park; S G, Rhee; C A, Kozak;

doi: 10.1007/s003359900151

pmid: 8672127

Genetic mapping of the human and mouse phospholipase C genes

Abstract

To determine chromosome positions for 10 mouse phospholipase C (PLC) genes, we typed the progeny of two sets of genetic crosses for inheritance of restriction enzyme polymorphisms of each PLC. Four mouse chromosomes, Chr 1, 11, 12, and 19, contained single PLC genes. Four PLC loci, Plcb1, Plcb2, Plcb4, and Plcg1, mapped to three sites on distal mouse Chr 2. Two PLC genes, Plcd1 and Plcg2, mapped to distinct sites on Chr 8. We mapped the human homologs of eight of these genes to six chromosomes by analysis of human x rodent somatic cell hybrids. The map locations of seven of these genes were consistent with previously defined regions of conserved synteny; Plcd1 defines a new region of homology between human Chr 3 and mouse Chr 8.

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Keywords

Genetic Markers, Base Sequence, Molecular Sequence Data, Chromosome Mapping, DNA Restriction Enzymes, Hybrid Cells, Polymerase Chain Reaction, Mice, Cricetinae, Type C Phospholipases, Animals, Humans, Chromosomes, Human, Pair 3, Crosses, Genetic, Polymorphism, Restriction Fragment Length, DNA Primers

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
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23
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