
The mouse genes encoding early growth response 4 (Egr4), annexin IV (Anx4), and transforming growth factor alpha (Tgfa) have been mapped to a linkage group on mouse chromosome 6 that is conserved on human chromosome 2p11-p13. The genes are closely linked, with 0/215 recombinants between Anx4 and Tgfa and 1/215 recombinants between these genes and Egr4. The genes are located approximately 2 cM distal to mnd2, a mouse mutation causing neuromuscular disease. The results demonstrate that mnd2 is located at an internal position within this conserved linkage group.
Recombination, Genetic, Genetic Linkage, Science, Molecular, Chromosome Mapping, Zinc Fingers, Neuromuscular Diseases, Transforming Growth Factor alpha, Mice, Biological Chemistry, Genes, Health Sciences, Genetics, Animals, Humans, Cellular and Developmental Biology, Annexin A4, Transcription Factors
Recombination, Genetic, Genetic Linkage, Science, Molecular, Chromosome Mapping, Zinc Fingers, Neuromuscular Diseases, Transforming Growth Factor alpha, Mice, Biological Chemistry, Genes, Health Sciences, Genetics, Animals, Humans, Cellular and Developmental Biology, Annexin A4, Transcription Factors
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