BindingDB Entry 50025107: Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.
BindingDB Entry 50025107: Identification of NVP-TAE684, a potent, selective, and efficacious inhibitor of NPM-ALK.
Small molecule binding data for protein ALK tyrosine kinase receptor, Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, JAK2/TYK2, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Lysyl-tRNA synthetase, Macrophage-stimulating protein receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot L7RSL3, O60674, P00519, P06213, P07948, P07949, P08581, P09619, P11362, P12931, P15127, P17948, P29597, P35968, P36888, P43403, P51813, P54760, P97793, Q02763, Q04912, Q15046, Q16620, Q541P7, and Q9UM73
ALK tyrosine kinase receptor, Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, JAK2/TYK2, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Lysyl-tRNA synthetase, Macrophage-stimulating protein receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Genomics Institute of the Novartis Research Foundation, Affinity
ALK tyrosine kinase receptor, Ephrin type-B receptor 4 (EphB4), Fibroblast growth factor receptor 1, Hepatocyte growth factor receptor, Insulin receptor, JAK2/TYK2, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Lysyl-tRNA synthetase, Macrophage-stimulating protein receptor, Neurotrophic tyrosine kinase receptor type 2, Platelet-derived growth factor receptor beta, SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase BMX, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase ZAP-70, Tyrosine-protein kinase receptor FLT3, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Genomics Institute of the Novartis Research Foundation, Affinity
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