BindingDB Entry 50036567: (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.

Name: BindingDB Entry 50036567: (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.
Creator: BindingDB
Keywords: Metabotropic glutamate receptor, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 3 (mGlu3), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and metabotropic glutamate 1/2, Royal Danish School of Pharmacy, Affinity

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Dataset . 2012

Data sources: Datacite

BindingDB Entry 50036567: (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.

Research datakeyboard_double_arrow_right Dataset 01 Jan 2012 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2w66mf9

BindingDB Entry 50036567: (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.

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Abstract

Small molecule binding data for protein Metabotropic glutamate receptor, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 3 (mGlu3), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and metabotropic glutamate 1/2, Uniprot P23385, P31422, P31423, P31424, P35349, P35400, and Q14416

Keywords

Metabotropic glutamate receptor, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 3 (mGlu3), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and metabotropic glutamate 1/2, Royal Danish School of Pharmacy, Affinity

19 Research products, page 1 of 2

BindingDB Entry 50044623: Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).
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BindingDB Entry 50045888: Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers.
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BindingDB Entry 50040712: Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.
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BindingDB Entry 50037647: Synthesis and preliminary biological evaluation of (2S,1'R,2'S)- and (2S,1'S,2'R)-2-(2'-phosphonocyclopropyl)glycines, two novel conformationally constrained l-AP4 analogues.
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BindingDB Entry 50037938: Synthesis and preliminary pharmacological evaluation of the four stereoisomers of (2S)-2-(2'-phosphono-3'-phenylcyclopropyl)glycine, the first class of 3'-substituted trans C1'-2'-2-(2'-phosphonocyclopropyl)glycines.
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BindingDB Entry 50015104: Synthesis, in vitro pharmacology, structure-activity relationships, and pharmacokinetics of 3-alkoxy-2-amino-6-fluorobicyclo[3.1.0]hexane-2,6-dicarboxylic acid derivatives as potent and selective group II metabotropic glutamate receptor antagonists.
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BindingDB Entry 50036404: Metabotropic glutamate receptors: novel targets for drug development.
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BindingDB Entry 50047305: New 4-Functionalized Glutamate Analogues Are Selective Agonists at Metabotropic Glutamate Receptor Subtype 2 or Selective Agonists at Metabotropic Glutamate Receptor Group III.
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BindingDB Entry 50039116: A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists.
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