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BindingDB Entry 50040712: Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.

Authors: BindingDB;

BindingDB Entry 50040712: Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.

Abstract

Small molecule binding data for protein Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 3A, Dopamine D1 and D2 receptor, Histamine H1 receptor, Metabotropic glutamate receptor, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 3 (mGlu3), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), Metabotropic glutamate receptor 8 (mGlu8), and metabotropic glutamate 1/2, Uniprot P05177, P08684, P11712, P21728, P23385, P25100, P31422, P31423, P31424, P35348, P35349, P35367, P35400, P70579, and Q14416

Keywords

Alpha-1A adrenergic receptor, Alpha-1D adrenergic receptor, Cytochrome P450 1A, Cytochrome P450 2C9, Cytochrome P450 3A, Dopamine D1 and D2 receptor, Histamine H1 receptor, Metabotropic glutamate receptor, Metabotropic glutamate receptor 2 (mGluR2), Metabotropic glutamate receptor 3 (mGlu3), Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), Metabotropic glutamate receptor 8 (mGlu8), and metabotropic glutamate 1/2, Sanford-Burnham Medical Research Institute, Affinity

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average