BindingDB Entry 50028767: Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.

Name: BindingDB Entry 50028767: Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.
Creator: BindingDB
Keywords: Metabotropic glutamate receptor, Metabotropic glutamate receptor 5, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, National Institute on Drug Abuse-Intramural Research Program, Affinity, 3. Good health

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Dataset . 2010

Data sources: Datacite

BindingDB Entry 50028767: Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.

Research datakeyboard_double_arrow_right Dataset 01 Jan 2010 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2k937fv

BindingDB Entry 50028767: Structure-activity relationships comparing N-(6-methylpyridin-yl)-substituted aryl amides to 2-methyl-6-(substituted-arylethynyl)pyridines or 2-methyl-4-(substituted-arylethynyl)thiazoles as novel metabotropic glutamate receptor subtype 5 antagonists.

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Abstract

Small molecule binding data for protein Metabotropic glutamate receptor, Metabotropic glutamate receptor 5, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, Uniprot P23975, P31424, P31645, P41594, and Q01959

Keywords

Metabotropic glutamate receptor, Metabotropic glutamate receptor 5, Serotonin and norepinephrine transporters (SERT/NET), Sodium-dependent dopamine transporter, and Sodium-dependent noradrenaline transporter, National Institute on Drug Abuse-Intramural Research Program, Affinity

18 Research products, page 1 of 2

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Structure−Activity Relationships Comparing N-(6-Methylpyridin-yl)-Substituted Aryl Amides to 2-Methyl-6-(substituted-arylethynyl)pyridines or 2-Methyl-4-(substituted-arylethynyl)thiazoles as Novel Metabotropic Glutamate Receptor Subtype 5 Antagonists
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BindingDB Entry 50017775: Design and synthesis of noncompetitive metabotropic glutamate receptor subtype 5 antagonists.
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BindingDB Entry 50048025: Development of 1
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BindingDB Entry 50017251: Phenyl ureas of creatinine as mGluR5 antagonists. A structure-activity relationship study of fenobam analogues.
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