BindingDB Entry 50015503: Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.

Name: BindingDB Entry 50015503: Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.
Creator: BindingDB
Keywords: Neuronal acetylcholine receptor subunit alpha-10/alpha-9, Neuronal acetylcholine receptor subunit alpha-2/beta-4, Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4, Neuronal acetylcholine receptor subunit alpha-3/beta-4, Neuronal acetylcholine receptor subunit alpha-4/beta-2, Neuronal acetylcholine receptor subunit alpha-4/beta-4, and Neuronal acetylcholine receptor subunit alpha-7, Hainan University, Affinity, 3. Good health

BindingDB

Found an issue? Give us feedback

https://dx.doi.org/1...arrow_drop_down

https://dx.doi.org/10.7270/q2r...

Dataset . 2023

Data sources: Datacite

BindingDB Entry 50015503: Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.

Research datakeyboard_double_arrow_right Dataset 01 Jan 2023 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2r78k4q

BindingDB Entry 50015503: Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors.

- Summary
- Subjects
- Related research
  (10)
- Metrics

Abstract

Small molecule binding data for protein Neuronal acetylcholine receptor subunit alpha-10/alpha-9, Neuronal acetylcholine receptor subunit alpha-2/beta-4, Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4, Neuronal acetylcholine receptor subunit alpha-3/beta-4, Neuronal acetylcholine receptor subunit alpha-4/beta-2, Neuronal acetylcholine receptor subunit alpha-4/beta-4, and Neuronal acetylcholine receptor subunit alpha-7, Uniprot P04757, P09483, P12389, P12390, P12392, P30926, P32297, P36544, P43144, Q05941, Q15825, and Q9JLB5

Related Organizations

University of California, San Diego
United States

Keywords

Neuronal acetylcholine receptor subunit alpha-10/alpha-9, Neuronal acetylcholine receptor subunit alpha-2/beta-4, Neuronal acetylcholine receptor subunit alpha-3/alpha-6/beta-4, Neuronal acetylcholine receptor subunit alpha-3/beta-4, Neuronal acetylcholine receptor subunit alpha-4/beta-2, Neuronal acetylcholine receptor subunit alpha-4/beta-4, and Neuronal acetylcholine receptor subunit alpha-7, Hainan University, Affinity

10 Research products, page 1 of 1

BindingDB Entry 50044001: Synthesis and pharmacological characterization of bivalent ligands of epibatidine at neuronal nicotinic acetylcholine receptors.
2014IsAmongTopNSimilarDocuments
BindingDB Entry 50044154: Design, synthesis, and biological evaluation of Erythrina alkaloid analogues as neuronal nicotinic acetylcholine receptor antagonists.
2015IsAmongTopNSimilarDocuments
BindingDB Entry 50013557: Computational and Functional Mapping of Human and Rat α6β4 Nicotinic Acetylcholine Receptors Reveals Species-Specific Ligand-Binding Motifs.
2022IsAmongTopNSimilarDocuments
Engineered Conotoxin Differentially Blocks and Discriminates Rat and Human α7 Nicotinic Acetylcholine Receptors
2021IsDerivedFrom
BindingDB Entry 50006208: Synthesis and Pharmacological Evaluation of DHβE Analogues as Neuronal Nicotinic Acetylcholine Receptor Antagonists.
2020IsAmongTopNSimilarDocuments
BindingDB Entry 50008162: PeIA-5466: A Novel Peptide Antagonist Containing Non-natural Amino Acids That Selectively Targets α3β2 Nicotinic Acetylcholine Receptors.
2021IsAmongTopNSimilarDocuments
BindingDB Entry 50000330: Highly Selective and Potentα4β2 nAChR Antagonist Inhibits Nicotine Self-Administration and Reinstatement in Rats.
2019IsAmongTopNSimilarDocuments
BindingDB Entry 50014483: Epibatidine structure-activity relationships.
2009IsAmongTopNSimilarDocuments
BindingDB Entry 50001142: TBA
2020IsAmongTopNSimilarDocuments
BindingDB Entry 50006317: Conformationally restrained carbamoylcholine homologues. Synthesis, pharmacology at neuronal nicotinic acetylcholine receptors and biostructural considerations.
2020IsAmongTopNSimilarDocuments

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average

Found an issue? Give us feedback

0

Average

Beta

SDGs Suggest

3. Good health

Beta

SDGs:

3. Good health,

Related to Research communities

Knowmad Institut