BindingDB Entry 50021018: L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.

Name: BindingDB Entry 50021018: L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.
Creator: BindingDB
Keywords: Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and Metabotropic glutamate receptor 8 (mGlu8), Université Paris Descartes, Affinity

BindingDB

Found an issue? Give us feedback

https://dx.doi.org/1...arrow_drop_down

https://dx.doi.org/10.7270/q2x...

Dataset . 2009

Data sources: Datacite

BindingDB Entry 50021018: L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.

Research datakeyboard_double_arrow_right Dataset 01 Jan 2009 English Publisher:BindingDB

Authors: BindingDB;

doi: 10.7270/q2xp74nq

BindingDB Entry 50021018: L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency.

- Summary
- Subjects
- Related research
  (10)
- Metrics

Abstract

Small molecule binding data for protein Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and Metabotropic glutamate receptor 8 (mGlu8), Uniprot P31423, P35349, P35400, and P70579

Keywords

Metabotropic glutamate receptor 4 (mGlu4), Metabotropic glutamate receptor 6 (mGlu6), Metabotropic glutamate receptor 7 (mGlu7), and Metabotropic glutamate receptor 8 (mGlu8), Université Paris Descartes, Affinity

10 Research products, page 1 of 1

BindingDB Entry 50045888: Synthesis and studies on the mGluR agonist activity of FAP4 stereoisomers.
2016IsAmongTopNSimilarDocuments
BindingDB Entry 50039116: A virtual screening hit reveals new possibilities for developing group III metabotropic glutamate receptor agonists.
2012IsAmongTopNSimilarDocuments
BindingDB Entry 50040712: Orally active metabotropic glutamate subtype 2 receptor positive allosteric modulators: structure-activity relationships and assessment in a rat model of nicotine dependence.
2013IsAmongTopNSimilarDocuments
BindingDB Entry 50007934: alpha-substituted quisqualic acid analogs: new metabotropic glutamate receptor group II selective antagonists.
2009IsAmongTopNSimilarDocuments
BindingDB Entry 7473: Hypophosphorous acid derivatives having antihyperalgic activity and biological applications thereof
2016IsAmongTopNSimilarDocuments
BindingDB Entry 50014149: (2S,1'S,2'R,3'R)-2-(2'-Carboxy-3'-hydroxymethylcyclopropyl) glycine is a highly potent group 2 and 3 metabotropic glutamate receptor agonist with oral activity.
2009IsAmongTopNSimilarDocuments
BindingDB Entry 50044623: Tetrahydronaphthyridine and dihydronaphthyridinone ethers as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).
2015IsAmongTopNSimilarDocuments
l-(+)-2-Amino-4-thiophosphonobutyric Acid (l-thioAP4), a New Potent Agonist of Group III Metabotropic Glutamate Receptors: Increased Distal Acidity Affords Enhanced Potency
2007IsDerivedFrom
BindingDB Entry 50036567: (S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.
2012IsAmongTopNSimilarDocuments
BindingDB Entry 50018085: Design and synthesis of APTCs (aminopyrrolidinetricarboxylic acids): identification of a new group III metabotropic glutamate receptor selective agonist.
2009IsAmongTopNSimilarDocuments

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	0
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average

Found an issue? Give us feedback

0

Average