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The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall

Authors: V.Y. Tseluyko; T.A. Lozova; V.P. Zheleznyy; O.S. Sasyuk;

The value of revascularization and adherence to therapy in the development of cardiovascular complications in long-term monitoring of patients with myocardial infarction of the right ventricle on the background of the Q-myocardial infarction of the left ventricular posterior wall

Abstract

The aim – to evaluate the role of deferred revascularization and adherence to drug therapy as factors affecting long-term prognosis of patients with myocardial infarction (MI) of the right ventricle (RV) on the background of the Q-myocardial infarction of the left ventricle (LV) posterior wall (PW). Materials and methods. The study involved 155 patients with MI of the RV due the Q-MI of the PWLV, age 64.11 ± 0.78 years. The revascularization (PCI, CABG) was performed within one year after MI. Adherence to treatment was assessed after 6 and 30 months. The combined endpoints included: unstable angina (UA), Re-MI, stroke and cardio-vascular (CV) death. Follow-up was 30.6 ± 4.5 month. Results. The 1st group included 68 (43.9 %) patients who underwent surgical treatment, 87 (56.1 %) patients under conservative strategy composed the 2nd group. The frequency of combined CV-point was significantly lower in the 1st group (ð = 0.00001). Revascularization after RV MI was accompanied by significant decrease of frequency of Re-MI (ð = 0.05), stroke (ð = 0.0413) and UA (ð = 0.00001) during 30 months follow-up. Reducing risk of CV events in the 1st group was associated with higher adherence to ACE inhibitors / ARA (86.7–79.4 %), statins (97.1–64.7 %) and clopidogrel (98.5–79.4 %) at 6 months and at the end of the observation period, compared to patients with conservative strategy (p < 0.05). Conclusions. Higher adherence to drug therapy in the surgical treatment group is associated with significantly lower number of cardiovascular events during 30 days after right ventricular myocardial infarction.

Keywords

myocardial infarction of the right ventricle, RC666-701, adherence to therapy, cardiovascular complications, Diseases of the circulatory (Cardiovascular) system, revascularization

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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