The holding of pharmacoeconomic studies of ACS with the use of ATC/DDD-methodology in order to optimize therapy, it is important. With the use of ATC/DDD-methodology, to estimate the treatment of 1071 patients with myocardial infarction. Тhe highest consumption of medicines groups Platelet aggregation inhibitors and Heparin group. The 3 place - nitrates, on 4 and 5 locations ACE inhibitors and beta-blockers. Behind them, on the level of consumption are diuretics and antithrombotic drugs. Listed group of drugs accounted for 90% of the volume of drug consumption in the analysis of DU90 by groups of medicines. In carrying out VEN-analysis of the data structure of groups of drug preparations, which are vitally necessary and attributed to the category V, amounted to 77.4% of essential drugs (category E) – 22,6%. Statins, which also belong to the category V, were not included in the group of DU-90%. So, ATC/DDD – methodology allows us to objectively assess the drug supply and significantly expands the capabilities of its analysis and may be widely used in practice.