A defect of the alternative pathway of complement.

J F, Soothill; B A, Harvey

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Clinical & Experimen...arrow_drop_down

Clinical & Experimental Immunology

Article . 1977

Data sources: Europe PubMed Central

A defect of the alternative pathway of complement.

descriptionPublicationkeyboard_double_arrow_right Article 27 May 1977 English Journal:Clinical and experimental immunology, volume 27 (issn: 0009-9104,

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Authors: J F, Soothill; B A, Harvey;

pmid: 321158

pmc: PMC1540913

A defect of the alternative pathway of complement.

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Abstract

The sera of patients defective at opsonization for yeast phagocytosis fix haemolytic complement poorly following incubation with the alternative pathway complement activators, inulin and bacterial endotoxin. This suggests that the defect lies early in the alternative pathway of complement.

Keywords

Adult, Complement Fixation Tests, Inulin, Infant, Complement System Proteins, Saccharomyces cerevisiae, Middle Aged, Opsonin Proteins, Endotoxins, Phagocytosis, Child, Preschool, Humans, Child

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	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%